Interdisciplinary PhD in Molecular Biosciences

Dr. Scott T. Handy - Publications

(* = undergraduate co-author)

  1. Piala, A.; Mayi, D.*; Handy, S.T. "One-pot, Regioselective Double Suzuki Couplings of Dibromoquinolines." Tetrahedron, In preparation.
  2. Chesak, S.; Handy, S.T. "One-pot Double Suzuki Couplings of 2,4-Dichloropyrimidine." Synthesis, In press.
  3. Ennis, E.G.; Handy, S.T.; Sanger, M.J.; Phelps, A.J. "Organic Chemistry Textbooks: The Core, the Extraneous, and the Uncertain." J. Chem. Ed. Submitted.
  4. Ennis, E.G.; Handy, S.T. "C2-Alkylation of Imidazolium Ionic Liquids." Molecules 2009.
  5. Ivanow, A.;* Handy, S.T. "Cyclopropanations using Electron-deficient Scorpionate-Copper Catalysts." Inorg. Chim. Acta, 2009, 362, 4468-4471. (Invited manucript for a special volume in memory of Swiatoslaw Trofimenko.)
  6. Handy, S.T.; Varallo, S.* "Regioselective Suzuki Couplings of Dibromothiophenes." Synthesis 2009, 138-142. (Invited manuscript for the special volume celebrating the 40th anniversary of Synthesis.)
  7. Mayi, D.;* Handy, S.T. "Regioselective Double Couplings of Dibromothiophene Aldehydes." Tetrahedron Lett. 2007, 46, 8108-8110.
  8. Wilson, T.; Muth, A.;* Handy, S.T. "Regioselective Double Couplings of Dibromopyridines." J. Org. Chem. 2007, 72, 8596-8500.
  9. Zhang, Y.; Handy, S.T. "A Solvent-induced Reversal of Regioselectivity in the Suzuki Coupling of Pyrrole Esters." Open Journal of Organic Chemistry 2008, 58-64.
  10. Manchanayakage, R.; Omune, D.; Hayes, C.; Handy, S.T. "Electrohydrocyclization of Alkoxy Tether Substituted Mixed Enone/Enoate and Bisenone Systems: Retention versus Elimination." Tetrahedron 2007, 63, 9691-9698.
  11. Ennis, E.; Handy, S.T. "The Chemistry of the C2 Position of Imidazolium Room Temperature Ionic Liquids." Curr. Org. Synth. 2007, 381-389.
  12. Manchanayakage, R.; Handy, S.T. "Regioselective Barbier reactions of 2-bromomethylcyclohexenones." Tetrahedron Lett. 2007, 48, 3819-3822.
  13. Handy, S.T.; Omune, D. "The Intramolecular Reductive Cyclization of Cyclic Enones." Tetrahedron 2007, 63, 1366-1371.
  14. Handy, S.T.; Zhang, Y. "Regioselective Couplings of Dibromopyrrole Esters." Synthesis 2006, 3883-3887.
  15. Handy, S.T. "One-pot Halogenation-Heck Coupling Reactions in Ionic Liquids." Synlett 2006, 3176-3178.
  16. Handy, S.T. "Grignard Reactions in Imidazolium Ionic Liquids." J. Org. Chem. 2006, 71, 4659-4662.
  17. Handy, S.T.; Sabatini, J.J.* "Regioselective Dicouplings: Application to Differentially Substituted Pyrroles." Org. Lett. 2006, 8, 1537-1539.
  18. Handy, S.T.; Ivanow, A.;* Czopp, M.* "Practical Aziridinations II: Electronic Modifications to Poly(pyrazolyl)borate-copper Catalysts." Tetrahedron Lett. 2006, 47, 1821-1823.
  19. Handy, S.T.; Zhang, Y. "A Simple Guide for Predicting Regioselectivity in the Coupling of Polyhaloheteroaromatics." Chem. Commun. 2006, 299-301.
  20. Handy, S.T.; Zhang, Y. "Approaches to the Synthesis of the Lamellarins and Related Natural Products. A Review." Org. Prep. & Proc. Int. 2005, 37, 411-445.
  21. Handy, S.T.; "Room Temperature Ionic Liquids: Different Classes and Physical Properties." Curr. Org. Chem. 2005, 9, 959-989.
  22. Handy, S.T.; Omune, D. "A Chelation Effect on the Pathway Between Intramolecular Hydrodimerization and Pinacol Coupling." Org. Lett. 2005, 7, 1553-1555.
  23. Handy, S.T.; Okello, M. "The 2-Position of Imidazolium Ionic Liquids: Substitution and Exchange." J. Org. Chem. 2005, 70, 1915-1918.
  24. Handy, S.T.; Okello, M. "Homogeneous Supported Synthesis Using Ionic Liquid Supports: Tunable Separation Properties." J. Org. Chem. 2005, 70, 2874-2877.
  25. Handy, S.T.; Sabatini, J.J.;* Zhang, Y.; Vulfova, I.* "Protection of Poorly Nucelophilic Pyrroles." Tetrahedron Lett. 2004, 45, 5057-5060.
  26. Handy, S.T.; Zhang, Y.; Bregman, H.* "A Modular Synthesis of the Lamellarins: Total Synthesis of Lamellarin G Trimethyl Ether." J. Org. Chem. 2004, 69, 2362-2366.
  27. Handy, S.T.; Okello, M. "Fructose-derived Ionic Liquids: Recyclable Homogeneous Supports." Tetrahedron Lett. 2003, 44, 8399-8402.
  28. Handy, S.T.; Okello, M. "Halide Effects on the Heck Reaction in Room Temperature Ionic Liquids." Tetrahedron Lett. 2003, 44, 8395-8397.
  29. Handy, S.T.; Okello, M.; Dickenson, G.* "Solvents from Biorenewable Sources: Ionic Liquids Based on Fructose." Org. Lett. 2003, 5, 2513-2515.
  30. Handy, S.T. "Greener Solvents: Room Temperature Ionic Liquids from Biorenewable Sources." Chem. Eur. J. 2003, 9, 2938-2944.
  31. Handy, S.T.; Bregman, H.;* Lewis, J.;* Zhang, X.; Zhang, Y. "An Unusual Dehalogenation in the Suzuki Coupling of 4-Bromopyrrole-2-carboxylates." Tetrahedron Lett. 2003, 44, 427-430.
  32. Handy, S.T.; Okello, M. "-Tosyloxyketones: Convenient [4+3] Cycloaddition Precursors." Synlett 2002, 489-491.
  33. Handy, S.T.; Czopp, M.* "Simple, Tunable Aziridination Catalysts Based on Poly(pyrazolyl)borate-Copper Complexes." Org. Lett. 2001, 3, 1423-1425.
  34. Handy, S.T.; Zhang, X. "Organic Synthesis in Ionic Liquids: The Stille Coupling." Org. Lett. 2001, 3, 233-236. [This manuscript has already been cited over 100 times.]
  35. Handy, S.T. "Asymmetric Catalysis: A Ligand's Eye View." Curr. Org. Chem. 2000, 4, 363-395.
  36. Wender, P.A.; Handy, S.T.; Wright, D.L. "Towards the Ideal Synthesis." Chem. & Ind. 1997, 765-769.
  37. Grieco, P.A.; Handy, S.T. "Magnesium Trifluoromethanesulfonimide (Triflimide) Promoted Substitution Reactions of Allylic and Benzylic Acetates. Magnesium Triflimide as a Substitute for Magnesium Perchlorate." Tetrahedron Lett. 1997, 38, 2645-2648.
  38. Barbarich, T.J.; Handy, S.T.; Miller, S.M.; Anderson, O.P.; Grieco, P.A.; Strauss, S.H. "LiAl(OC(Ph)(CF3)2)4: A Hydrocarbon-Soluble Catalyst for Carbon-Carbon Bond-Forming Reactions." Organometallics 1996, 15, 3776-3778.
  39. Grieco, P.A.; Collins, J.L.; Handy, S.T. "Ionic Diels-Alder Reactions in Lithium Perchlorate-Diethyl Ether." Synlett 1995, 1155-1157.
  40. Handy, S.T.; Grieco, P.A.; Mineur, C.; Ghosez, L. "Lithium Trifluoromethanesulfonimide in Acetone or Diethyl Ether as a Safe Alternative to Lithium Perchlorate in Diethyl Ether for Effecting Diels-Alder Reactions. Unexpected Influence of the Counterion on Exo/Endo Selectivity." Synlett 1995, 565-567.
  41. Grieco, P.A.; Beck, J.P.; Handy, S.T.; Saito, N.; Daeuble, J.F. "Acid Catalyzed Intramolecular Diels-Alder Reactions in Lithium Perchlorate-Diethyl Ether: Acid Promoted Migration of Terminal Dienes Prior to [4+2] Cycloaddition in Conformationally Restricted Substrates." Tetrahedron Lett. 1994, 35, 6783-6786.
  42. Grieco, P.A.; Handy, S.T.; Beck, J.P. "Acid Catalyzed Intramolecular Diels-Alder Reactions in Lithium Perchlorate-Diethyl Ether: Enhanced Reaction Rates and Diastereoselectivity." Tetrahedron Lett. 1994, 35, 2663-2666.