Interdisciplinary PhD in Molecular Biosciences

Dr. Paul C. Kline - Publications

Farone, A.; Farone, M.; Kline, P.; Quinn, T.; Sinkala, Z. A Practical Approach for Computing the Active Site of the Ribonucleoside Hydrolase of E. coli Encoded by rihC Advances in Computational Biology (Advances in Experimental Medicine and Biology Series) Vol 680, August 2010

Kline, P.C.; Zhao, H.Q.; Noll, B.C.; Serianni, A.S. 1-(b-D-Erythrofuranosyl)adenosine. Acta Crystallographica Section C Crystal Structure Communications 2010, C66, 215-218.

Merkler, David J.; Asser, Alexander S.; Baumgart, Laura E.; Carballo, Natalie; Carpenter, Sarah E.; Chew, Goeffrey, H.; Cosner, Casey C.; Dusi, Jodi; Galloway, Lamar C.; Lowe, Andrew B.; Lowe, Jr. Edward W.; King III, Lawrence; Kendig, Robert D.; Kline, Paul C.; Malka, Robert; Merkler, Kathleen A.; McIntyre, Neil R.; Romero, Mindy; Wilcox, Benjamin J.; Owen, Terence C. Substituted Hippurates and Hippurate Analogs as Substrates and Inhibitors of Peptidylglycine -Hydroxylating Monooxygenase (PHM). Bioorganic and Medicinal Chemistry 2008, 16 10061-10074.

"Extraction of a Lipid from Nutmeg", Tammy J. Melton and Paul C. Kline. Cach? House Publishers, labPass Database, www.Cachehouse.com, 2007.

"Spectral Analysis of Beef Extract", Tammy J. Melton and Paul C. Kline. Cach? House Publishers, labPass Database, www.Cachehouse.com, 2007.

"Identification of Disaccharides", Tammy J. Melton and Paul C. Kline. Cach? House Publishers, labPass Database, www.Cachehouse.com, 2007.

Kline, P.C.; Noll, B.C.; Zhao, H.; Serianni, A.S. 1-(b-D-Erythrofuranosyl)cytidine (b-erythrocytidine). Acta Crystallographica Section C Crystal Structure Communications 2007, C63, 137-140.

Bates C.; Z. Kendrick Z.; McDonald, N; Kline, P. C. Transition State Analysis of Adenosine Nucleosidase from Yellow Lupin ( LupinuslLuteus). Phytochemistry 2006, 67, 5-12.

Hunt, C.; Gillani, N.; Farone, A.; Rezaei, M.; Kline, P.C. Kinetic Isotope Effects of Nucleoside Hydrolase from Escherichia coli. Biochim. Biophys. Acta Proteins and Proteomics 2005, 1751, 140-149.

Abusamhadneh, E.; McDonald, N. E.; Kline, P. C. Purification and characterization of adenosine nucleosidase form yellow lupin ( Lupinus luteus). Plant Sci. 2000, 153, 25-32.

Verdel, E. F.; Kline, P. C.; Wani, S.; Woods, A. E. Purification and partial characterization of haloperoxidase from fresh water algae Cladophora glomerata. Comp. Biochem. Physiol. B 2000, 125, 179-187.

Kline, P. C.; Razaei, M.; Lee, T. A. Determination of Kinetic Isotope Effects for Nucleoside Hydrolases using Gas Chromatography/Mass Spectrometry. Anal. Biochem. 1999, 275, 6-10.

Schramm, V. L.; Horenstein, B. A.; Bagdassarian, C. K.; Schwartz, S. D.; Berti, P. J.; Rising, K. A.; Scheuring, J.; Kline, P. C.; Parkin, D. W.; Merkler, D. Enzymatic Transition States and Inhibitor Design from Principles of Classical and Quantum Chemistry. Int. J. Quantum Chem. 1996, 23, 81-89.

Kline, P. C.; Schramm, V. L. Pre-Steady State Transition State Analysis of the Hydrolytic Reaction Catalyzed by Purine Nucleoside Phosphorylase. Biochemistry 1995, 34, 1153-1162.

Schramm, V. L.; Horenstein, B. A.; Kline, P. C. Transition State Analysis and Inhibitor Design for Enzymatic Reactions. J. Biol. Chem. 1994, 269, 18259-18262.

Schramm, V. L.; Kline, P. C. Electrostatic Potential Surfaces of the Transition State for AMP Deaminase and for (R)-Coformycin, a Transition State Inhibitor. J. Biol. Chem. 1994, 269, 22385-22390.

Kline, P. C.; Schramm, V. L. Purine Nucleoside Phosphorylase.? Catalytic Mechanism and Transition State Analysis of the Arsenolysis Reaction. Biochemistry 1993, 32, 13212-13219.

Merkler, D. J.; Kline, P. C.; Weiss, P.; Schramm, V. L. Transition State Analysis of AMP Deaminase. Biochemistry 1993, 32, 12993-13001.

Kline, P. C.; Schramm, V. L. Purine Nucleoside Phosphorylase.? Inosine Hydrolysis, Tight Binding of the Hypoxanthine Intermediate, and Third-the-Sites Reactivity. Biochemistry 1992, 31, 5964-5973.

Kline, P. C.; Serianni, A. S. Synthesis and Conformational Analysis of Isotopically Enriched Erythronucleosides. J. Org. Chem. 1992, 57, 1772-1777.

Serianni, A. S.; Kline, P. C.; Snyder, J. R. On the Use of Model Compounds to Assess 2-Deoxy-D-Erythropentofuranose Conformation at Apyrimidinic Sites in DNA.? J. Am. Chem. Soc. 1990, 112, 5886-5887.

Kline, P. C.; Serianni, A. S.; Huang, S. G.; Hayes, M.; Barker, R. Proton-Proton Internuclear Distance Measurements in Carbohydrates:? Proton Transient Nuclear Overhauser Enhancement and Spin-Lattice Relaxation in Carbon-13 and Deuterium-Substituted Compounds. Can. J. Chem. 1990, 68, 2171-2182.

Kline, P. C.; Serianni, A. S. 13C-Enriched Ribonucleosides:? Synthesis and Application of 13C-1H and 13C-13C Spin-Coupling Constants to Assess Furanose and N-Glycoside Bond Conformations. J. Am. Chem. Soc. 1990, 112, 7373-7381.

Kline, P. C.; Serianni, A. S. Chiral Hydroxymethyl Groups:? Proton NMR Assignments of the Prochiral C5' Protons of 2'-Deoxyribonucleosides. Magn. Reson. Chem. 1990, 28, 324-330.

Kline, P. C.; Serianni, A. S. Chiral Hydroxymethyl Groups:? Proton NMR Assignments of the Prochiral C5'- Protons of Ribonucleosides. Magn. Reson. Chem. 1988, 26, 120-123.

Myerson, A.; Kline, P. Continuous Bacterial Coal Desulfurization Employing Thiobacillus ferrooxidans. Biotechnology Bioengineering 1984, 26, 92-99.

Myerson, A.; Kline, P. The Adsorption of Thiobacillus ferrooxidans on Solid Particles. Biotechnology Bioengineering 1983, 25, 1669-1676.