Faculty and Staff

Dr. Mengliang Zhang

Assistant Professor

Dr. Mengliang Zhang
(615) 904-8439
Room 3155, Science Building (SCI)
MTSU Box 68, Murfreesboro, TN 37132

Degree Information

  • Ph.D., Ohio University (2015)
  • M.S., Jilin University (2010)
  • B.S., Jilin University (2007)

Areas of Expertise

Instrumental analysis, chemometrics, forensic analysis, food analysis

Publications

[1]  Zhang, M.;* Sun, J.;* Chen, P., Development of a Comprehensive Flavonoid Analysis Computational Tool for Ultrahigh-Performance Liquid Chromatography-Diode Array Detection-High-Resolution Accurate Mass-Mass Spectrometry Data. Analytical Chemistry 2017, 89(14), 7388–7397 DOI: 10.1021/acs.analchem.7b00771

[2]  Sun, J.; Liu, W.; Zhang, M.; Geng, P.; Shan, Y.; Li, G.; Zhao, Y.; Chen, P., The Analysis of Phenol...

Read More »

[1]  Zhang, M.;* Sun, J.;* Chen, P., Development of a Comprehensive Flavonoid Analysis Computational Tool for Ultrahigh-Performance Liquid Chromatography-Diode Array Detection-High-Resolution Accurate Mass-Mass Spectrometry Data. Analytical Chemistry 2017, 89(14), 7388–7397 DOI: 10.1021/acs.analchem.7b00771

[2]  Sun, J.; Liu, W.; Zhang, M.; Geng, P.; Shan, Y.; Li, G.; Zhao, Y.; Chen, P., The Analysis of Phenolic compounds in Daylily using UHPLC-HRMSn and Evaluation of Drying Processing Method by Fingerprinting and Metabolomic Approaches. Journal of Food Processing and Preservation, 2017, 00:e13325. DOI: 10.1111/jfpp.13325

[3]  Geng, P.; Harnly, J.; Sun, J.; Zhang, M.; Chen, P., Feruloyl dopamine-O-hexosides are efficient marker compounds for differentiation between Black Cohosh (Actaea racemosa) and related Actaea species-an UHPLC-HRAM-MS Chemometrics Study. Analytical and Bioanalytical Chemistry, 2017, 409(10), 2591-2600. DOI: 10.1007/s00216-017-0205-1

[4]  Zhang, M.;* Sun, J.;* Chen, P., A Computational Tool for Accelerated Analysis of Oligomeric Proanthocyanidins in Plants. Journal of Food Composition and Analysis, 2017, 56, 124-133. DOI: 10.1016/j.jfca.2016.11.014

[5]  Geng, P.; Sun, J; Zhang, M.; Li, X; Harnly, J.; Chen, P., Comprehensive Characterization of C-glycosyl Flavones in Wheat (Triticum aestivum L.) Germ Using UPLC-PDA-ESI/HRMSn and Mass Defect Filtering. Journal of Mass Spectrometry 2016, 51, 914-930. DOI: 10.1002/jms.3803

[6]  Sun, J.;* Zhang, M.;* Chen, P., GLS-Finder: An Automated Data-Mining System for Fast Profiling Glucosinolates and its Application in Brassica Vegetables. Journal of Agriculture and Food Chemistry, 2016, 64(21), 4407-4415. DOI: 10.1021/acs.jafc.6b01277.

[7]  Zhang, M.; Zhao, Y.; Harrington, P. B.; Chen, P., Differentiation of Aurantii Fructus Immaturus and Fructus Poniciri Trifoliatae Immaturus by Flow-Injection with Ultraviolet Spectroscopic Detection and Proton Nuclear Magnetic Resonance using Partial Least-squares Discriminant Analysis. Analytical Letters 2016, 49(5), 711-722. DOI: 10.1080/00032719.2015.1045588

[8]  Zhang, M.; Kruse, N. A.; Bowman, J. R.; Jackson, G. P., Field Analysis of Polychlorinated Biphenyls (PCBs) in Soil using a Portable Solid Phase Microextraction (SPME) and Gas Chromatograph/Mass Spectrometry System. Applied Spectroscopy 2016, 70, 785-793.

[9]  Zhang, M.;* Sun, J.;* Chen, P., FlavonQ: An "Expert System" Automated Data Processing Tool for Profiling Flavone/flavonol Glycosides Using Ultra High-performance Liquid Chromatography Diode Array Detection and High-Resolution Accurate-Mass Mass Spectrometry (UHPLC HRAM-MS). Analytical Chemistry 2015, 87(19), 9974–9981 DOI: 10.1021/acs.analchem.5b02624.

[10]  Geng, P.; Zhang, M.; Harnly, J.; Luthria, D.; Chen, P., Differentiation of Whole Grain and Refined Wheat (T. aestivum) Flour Using Fuzzy Chromatography Mass Spectrometric (FCMS) Fingerprinting and Chemometric Approaches. Analytical and Bioanalytical Chemistry 2015, 1-14. DOI:10.â��1007/â��s00216-015-9007-5 (Selected as Paper in Forefront.)

[11]  Zhang, M.; Harrington, P. B.; Chen, P, Classification of Cultivation Locations of Black Pepper (Piper nigrum L.) using Gas Chromatography and Chemometrics. Current Chromatography 2015, 2(2), 145-151. DOI: 10.2174/2213240602666150518235059

[12]  Zhang, M.; Harrington, P. B., Determination of Trichloroethylene in Water by Liquid–Liquid Microextraction Assisted Solid Phase Microextraction. Chromatography 2015, 2, 66-78. DOI:10.3390/chromatography2010066

[13]  Zhang, M.; Harrington, P. B., Application of Chemometrics to Resolve Overlapping Mass Spectral Peak Clusters Between Trichloroethylene and its Deuterated Internal Standard. Rapid Communications in Mass Spectrometry 2015, 29, 789-794. DOI: 10.1002/rcm.7164

[14]  Wang, Z.; Zhang, M.; Harrington, P. B., A Comparison of Three Algorithms for the Baseline Correction of Hyphenated Data Objects. Analytical Chemistry 2014, 86, 9050-9057. DOI: 10.1021/ac501658k

[15]  Zhang, M.; Harrington, P. B., Simultaneous Quantification of Aroclor Mixtures in Soil Samples by Gas Chromatography/Mass Spectrometry with Solid Phase Microextraction using Partial Least-Squares Regression. Chemosphere 2014, 118C, 187-193. DOI: 10.1016/j.chemosphere.2014.08.018.

[16]  Zhang, M.; Jackson, G. P.; Kruse, N. A.; Bowman, J. R.; Harrington, P. B., Determination of Aroclor 1260 in Soil Samples by GC/MS with Solid Phase Microextraction. Journal of Separation Science 2014, 37, 2751-27566. DOI: 10.1002/jssc.201400102.

[17]  Gu, J.; Zhang, Y.; Shi, M.; Zhang, M.; Cheng, L.; Sun, H.; Wang, C.; Sun, Y.; Yang, Y., Regional and Systemic Distribution of Temozolomide from a Polymer Implant in Rat Brain, Drug Metabolism Reviews 2014, 45, 94-94.

[18]  Zhang, M.; Harrington, P. B., Automated pipeline for classifying Aroclors in soil by gas chromatography/mass spectrometry using modulo compressed two-way data objects. Talanta 2013, 117, 483-491.

[19]  Wu, X.; Zhang, M.; Cui, X.; Paul Fawcett, J.; Gu, J., Comparative pharmacokinetics and the bioavailability of escin Ib and isoescin Ib following the administration of escin, pure escin Ib and isoescin Ib in rats. Journal of Ethnopharmacology 2014, 151(2), 839-845

[20]  Wu, X.; Zhang, M.; Cui, X.; Gao, F.; He, Q.; Li, X.; Zhang, J.; Fawcett, J. P.; Gu, J., Comparative pharmacokinetics and bioavailability of escin Ia and isoescin Ia after administration of escin and of pure escin Ia and isoescin Ia in rat. Journal of Ethnopharmacology 2012, 139(1), 201-6.

[21]  Zhang, M.; Wu, X.; Cui, X.; Gao, F.; Zhang, C.; Yang, Y.; Gu, J., Simultaneous Determination of Escin Ia and Its Isomer Isoescin Ia by LC-MS-MS: Application to a Pharmacokinetic Study of Escin Ia in Rats. Chromatographia 2011, 74(3-4), 243-250.

[22]  Zhang, M.; Gao, F.; Cui, X.; Zhang, Y.; Sun, Y.; Gu, J., Development and Validation of an Improved Method for the Quantitation of Sertraline in Human Plasma using LC-MS-MS and Its Application to Bioequivalence Studies. Journal of Chromatographic Science 2011, 49(2), 89-93.

[23]  Cui, X.; Zhang, M.; Guan, X.; Yin, L.; Sun, Y.; Fawcett, J. P.; Gu, J., LC-MS-MS Determination of Troxerutin in Plasma and Its Application to a Pharmacokinetic Study. Chromatographia 2011, 73 (1-2), 165-169.

[24]  Wu, X.; Liu, L.; Zhang, M.; Wu, D.; Wang, Y.; Sun, Y.; Fawcett, J. P.; Gu, J.; Zhang, J., Simultaneous analysis of isomers of escin saponins in human plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study after oral administration. Journal of Chromatography B 2010, 878(11-12), 861-867.

[25]  Sun, Y.; Guo, Y.; Zhang, M.; Cui, X.; Gu, J., Effect of novel β2 receptor agonist trantinterol on cytochrome P450 mRNA expression in HepG2 cells. Journal of Jilin University (Medicine Edition) 2010, 36(5), 862-865.

[26]  Sun, Y.; Gao, F.; Zhang, M.; Cui, X.; Wang, Z.; Gu, J., Effect of trantinterol on cytochrome P450 enzymes. Journal of Jilin University (Science Edition). 2010, 6, 1061-1064. [27]  Gao, F.; Zhang, M.; Cui, X.; Wang, Z.; Sun, Y.; Gu, J., Simultaneous quantitation of hydrochlorothiazide and metoprolol in human plasma by liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 2010, 52(1), 149-154.

*Co-first author

« Read Less

Awards

2016                      John A. Milner Fellow by BHNRC, USDA and ODS, NIH.

2014                      Tomas A. Hirschfeld Scholar Award from Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) 2014 SciX.

2014       &n...

Read More »

2016                      John A. Milner Fellow by BHNRC, USDA and ODS, NIH.

2014                      Tomas A. Hirschfeld Scholar Award from Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) 2014 SciX.

2014                      1st place Award for Sigma Xi Section in 2014 Ohio University Student Expo.

2013                      Outstanding Teaching Assistant of the Year Award, College of Arts and Sciences, Ohio University, US. 

2010                      Outstanding Master Student Award, College of Life Science, Jilin University, China. 

« Read Less

Courses

Quantitative Analysis 2230/2231 (2017 Fall)